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In addition to boosting GLP-1, the GLP-1/GIP agonist tirzepatide (Zepbound) mimics the hormone gastric inhibitory polypeptide (GIP), which has similar effects to those of GLP-1

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WHO recommends long-term treatment for obesity with GLP-1s in first-ever guidelines The guidelines highlight a shift to viewing obesity as a chronic illness, but safety evidence for GLP-1s remains limited