According to some publications, the extent and the intensity of physiological oral mucosal melanin hyperpigmentation increase with age probably owing to the cumulative effects of endogenous and extrinsic melanogenic stimuli, such as inflammatory processes, drugs, tobacco smoke, and recurrent minor functional injuries [4, 6, 11, 13]
(2012) demonstrated that long-term exposure to CP impaired autophagy leading to CP resistance, and interestingly, upregulation of autophagic response under such condition re-sensitized resistant cells to CP-induced cell death
Biomarker assessment informs whether supplementation addresses a documented need or represents preventive approach for low-risk individuals
While several editorials have expressed concern regarding the disproportionate reporting of retinal adverse events associated with GLP-1 RA use in specific studies, there remain a number of broad limitations
Additionally, its involvement in managing stress and reducing anxiety could potentially contribute to enhancing sleep quality