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Meal timing: Eating within an hour of waking helps prevent morning nausea from becoming severe

It is important to note that Phase 2 trials typically exclude participants with significant cardiovascular disease, which limits the generalisability of these safety findings to higher-risk populations

However, rapid weight loss with semaglutide can lead to loss of lean muscle mass

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There are no randomized controlled trials (RCTs) exploring this question, and only a small number of observational studies have assessed outcomes after treatment switch [13, 14]