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These medicines include injectable formulations such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Byetta, Bydureon BCise), as well as oral semaglutide (Rybelsus)

The majority of patients (86%) had diabetes, and all had a Hidradenitis Suppurativa Physicians Global Assessment (HS-PGA) score of 1 or higher

Storgaard H, Cold F, Gluud LL, Vilsboll T, Knop FK

A clinically relevant effect will depend on the extent of PK changes and the therapeutic index of the co-administered oral drug

Misfolded -synuclein can be released extracellularly, activating microglia and spreading pathogenic seeds or DAMPs to neighboring neurons, amplifying degeneration