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Alexis Cutchins: Sleep is a tricky one
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At steady state, the exposure (in terms of AUC 0168 h,SS , C avg and C max,SS ) of semaglutide 1.0 mg appeared to be approximately double that of semaglutide 0.5 mg, while clearance and distribution appeared similar for both doses
Your healthcare provider may wish to: Perform blood tests to exclude anaemia, thyroid dysfunction, vitamin deficiencies, electrolyte imbalances, or renal impairment Review your medication regimen for potential drug interactions or side effects from other medications Assess whether dose adjustment of Wegovy is appropriatethe titration schedule can be slowed by an additional 4 weeks or the dose temporarily reduced if side effects are problematic [1] Consider alternative causes of fatigue unrelated to Wegovy NICE guidance (TA875) emphasises the importance of ongoing monitoring during weight management interventions
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