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Thus, HCC cells can internalize extracellular proteins by increasing the expression of a membrane ruffling protein called EH domain-containing protein 2, leading to resistance to glutamine deprivation under hypoxic conditions 122
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[PMID: 4017254] PubMed record related to this compound for laboratory literature review
PLoS Pathog (2011) 7:e1001271.10.1371/journal.ppat.1001271 Summary Keywords inflammation, innate immunity, TLR4, macrophages, glutathione, redox regulation, antiviral immunity, influenza Citation Diotallevi M, Checconi P, Palamara AT, Celestino I, Coppo L, Holmgren A, Abbas K, Peyrot F, Mengozzi M and Ghezzi P (2017) Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties