A pre-bed dose, taken once the stomach has emptied, is timed to reinforce that nocturnal pulse
Gynecol Endocrinol 2019;35(3):198-206 Fruzzetti F, Perini D, Russo M, Bucci F, Gadducci A
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The researchers even did brain scans and concluded that being unknowingly slipped about 200 mg of quinine not only affected how much the study participants felt like they wanted to eat, but how much they actually did eat, by interfering with reward brain circuits