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PCRs were performed in triplicate for each cDNA, averaged, and normalized to endogenous actin reference transcripts
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Even with reduced appetite, some patients compensate by eating calorie-dense foods during the eating windows that semaglutide creates
In the -cell, PC1/3 is up-regulated, resulting in increased processing of proglucagon to GLP-1 while DPP-4 is down-regulated in order to reduce degradation and enhance local intact GLP-1 concentrations
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