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Zhang M, Nomura A, Uchida Y, et al

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However, recent studies have revealed the potential for these compounds to also impact the pathological process of AD

For example, at doses of 5060 g, 100% of participants were reported to experience gastrointestinal distress, whereas with 30 g only a few participants experienced mild gastrointestinal effects (81)

Advise patients on the symptoms of hypersensitivity reactions and instruct them to stop taking RYBELSUS and seek medical advice promptly if such symptoms occur [see Warnings and Precautions (5.7)]