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Similarly, inhibition of CD38 in aged mice boosted NAD + levels, improving exercise capacity, but in this case, no significant changes in mitochondrial biogenesis-related genes were observed 138

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The RNA-seq and qRT-PCR results for both up- and downregulated genes showed a strong positive association (r = 0.854, p = 0.007

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The GHRP family tree The GH secretagogue research program that produced GHRP-6 also spawned several related compounds: GHRP-1: The earliest compound in the series