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While IOP remained unaffected, SPE treatment effectively attenuated oxidative stress and inflammation, as evidenced by reduced levels of 4-HNE, IL-6, and pNF-B
Effect of proanthocyanidin, arginine and glutamine supplementation on methotrexate-induced gastrointestinal toxicity in rats
Denzoin LA et al
S.SchoenenJ.et al (2021)
Unlike other antidiabetic drugs that cause the pancreas to secrete more insulin, metformin makes the bodys tissues more sensitive to insulin, thus reducing insulin resistance (Nasri 2014)
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