Interestingly, the study did find that sublingual GSH led to slightly greater glutathione levels compared to NAC, but both did increase levels
Key risks include: Delayed appropriate treatment : Patients with type 2 diabetes or obesity may postpone evidence-based interventions while using ineffective patches, potentially worsening metabolic control and increasing cardiovascular risk Undisclosed ingredients : While supplement manufacturers must follow current Good Manufacturing Practices, quality control varies widely
Most gastrointestinal side effects diminish significantly after 48 weeks of continuous treatment at a stable dose, though individual experiences vary considerably
36 in healthy participants
Publication Details Wang W, Davis PB, Qi X, Gurney M, Perry G, Volkow ND, Kaelber DC, Xu R