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Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Precautions (5.7) and Drug Interactions (7.1)]

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For instance, in a systematic review of such a relationship in adults, a significant negative correlation of about 0.3 between mean chronological age and mean LTL was found across 124 cross-sectional studies (Mezzinler et al., 2013)

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