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Struggling with Weight Loss
Could creatine become an important addition for people taking GLP-1 medications
semaglutide is the only one approved for obesity treatment Type 2 diabetes with cardiovascular risk Semaglutide Proven 20% MACE reduction in SELECT (obesity) and 26% in SUSTAIN 6 (T2D), while exenatide only achieved non-inferiority in EXSCEL Budget-conscious diabetes treatment Exenatide Lower cost and generic availability make exenatide accessible when newer agents are unaffordable or not covered by formulary Oral medication preference Semaglutide Rybelsus (oral semaglutide) offers injection-free GLP-1 therapy
J Clin Invest 127:2432
I also tell them animal studies are not human studies and do not correlate. The medical saga of thalidomide, which was tied to severe birth defects when taken during pregnancy in the late 1950s and early 1960s, initially appeared to be safe in animal studies
