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placebo: 2% (1/51), 95% CI: 010%) and AEs leading to discontinuation (apitegromab: 4% (2/51), 95% CI: 113%
Early intervention: Preserves collagen reserves Reduces severity of laxity Improves longterm firmness Often reduces need for corrective procedures later Think of this as preventative aesthetics the same principle used in musculoskeletal rehabilitation
10.1136/ard.2008.101279 23 MurrayC
5 Conclusions and future perspectives Dietary modulation remains a cornerstone in the management of CC, underpinned by robust mechanistic evidence linking nutrients, hormones, BAs, and the gut-brain-microbiota axis
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