Liposomal GSH, which is composed of tiny spheres of phospholipids, similar to the Trojan horse, encapsulates (or shields) the glutathione (GSH) with a lipid coating that protects it from being broken down by enzymes
[31] [32] [33] Similarly, in humans, renal proximal tubular cells contain high concentrations of alpha GST, while distal tubular cells contain pi GST
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Adang AE, Brussee J, van der Gen A, Mulder GJ
Notably, combination with anti-PD-1 checkpoint blockade yields synergy, significantly enhancing the ICB responsiveness of TNBC and producing improved therapeutic efficacy