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Lipolysis Enhancement and Lipogenesis Inhibition In obese Zucker rats, daily oral administration of AOD9604 significantly increased lipolytic activity in adipose tissue compared to controls, establishing direct adipocyte-level lipolysis stimulation as a key mechanism of action in pre-clinical models

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Localized dermal regeneration studies use 500mcg to 1mg administered subcutaneously every 48 hours, anti-inflammatory models use 200mcg to 500mcg daily or every other day, and systemic collagen synthesis protocols use 1mg to 2mg every 72 hours for multi-week studies