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Its molecular target is nicotinamide N-methyltransferase (NNMT), a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, consuming SAM and releasing S-adenosylhomocysteine
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D.et alTECOS Study Group (2017)
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A C20 fatty diacid is attached to enable albumin binding and weekly dosing
Relevant conclusions or results were extracted from each article to provide a narrative review
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