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NICE recommends GLP-1 receptor agonist medications for adults with type 2 diabetes who haven't achieved adequate glycaemic control with lifestyle changes and other treatments, or for obesity management when specific BMI and comorbidity criteria are met
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The GLP-1R/GIPR/GcgR triple-agonist retatrutide achieves body weight loss (~25%) in just two-thirds of the time, potentially surpassing the efficacy of Roux-en-Y gastric bypass [29]
Ice as a last resort If you consistently find injections painful despite proper technique, try applying an ice cube or cold pack to the injection site for 30 to 60 seconds before injecting
This would result in the optimization of both, patient-related and procedural, outcomes
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