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Ethics declarations Competing interests The authors declare that they have no known competing financial interests or personal relationship that could have appeared to influence the work reported in this article

Sleep disruption can occur, especially in a calorie deficit

Metabolic and Glycemic Effects of Orforglipron, a GLP 1 Receptor Agonist, in Adults With or Without Diabetes: A Network MetaAnalysis of Randomised Clinical Trials , Endocrinology, Diabetes & Metabolism, 9 , 4, (2026)

This stepwise approach improves adherence rates and helps your body adjust to the metabolic changes that GLP-1 medications produce

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