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Comparison to Other GLP-1 Medications Retatrutide's BP reduction exceeds other obesity medications: Semaglutide (Wegovy): -6.2 mmHg systolic Tirzepatide (Zepbound): -8.0 mmHg systolic (15mg, SURMOUNT-1) Retatrutide: -14.0 mmHg systolic The addition of glucagon receptor agonism likely contributes
Research Glucagon-like peptide-1 receptor: mechanisms and advances in therapy Zheng Z, Zong Y, Ma Y, Tian Y, Pang Y, Zhang C, Gao J
Tian, S
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