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Jan 23 2021;397(10271):319-333
However, it is not known whether these mechanisms are direct, central actions of SGLT-2is may be one of the essential links to the clinical improvement of RAAS and sympathetic activation in cardiovascular conditions like chronic heart failure in T2D
In preclinical studies, it has been estimated that about 20% of the total energy needs of the adult brain may be met by fatty acid oxidation occurring in astrocytes [33]
Epub 2016 Jun 13
Oral bioavailability is just a fancy way of asking whether the drug survives the babys stomach and reaches their bloodstream
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