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Glucagon agonism in the treatment of metabolic diseases including type 2 diabetes mellitus and obesity
It works through two mechanisms: inhibiting the enzyme tyrosinase (which is essential for melanin synthesis) and shifting the melanin production pathway from eumelanin (darker pigment) to pheomelanin (lighter pigment)
Hung, L
Combining PGA and Kyn/Trp ratio improved discriminatory performance, yielding an AUC of 0.84 for patient/control comparisons (Supplemental Information, Fig
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