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While healthy fibroblasts maintain healthy tissue structure, pro-fibrotic fibroblasts support fibrosis

No injection, no skin transfer risk, no cold chain

Who Should and Should Not Consider GLP-1 Therapy With Crohn's Disease Candidates for GLP-1 therapy with Crohn's disease typically have well-controlled or remission-stage disease, stable inflammatory markers, adequate nutritional status, and documented need for weight management

However, medical experts caution that peptides like retatrutide come with real risks

Monitoring focuses on glucose handling, IGF-axis context, cardiovascular risk, and symptoms that may suggest excessive pathway activity