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they do not demonstrate benefit

(It appears to be a fragment of a larger gastric protein, but no one has traced it to a human gene

There are still many open questions regarding the metabolism and toxicity of OTA, including whether OTA is activated to electrophilic metabolites that can then bind to DNA, proteins, and other cellular molecules

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This difference in the reaction product occurs even though the immediate Fe(II) coordination environment is the same in both enzyme types