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We found consistent effects of ALC significantly reducing serum ammonia level and improving NCT in patients with West Haven grade 0, 1, 2 and 3 encephalopathy versus placebo prompting that ALC may be comparable to the current medications of HE, such as non-absorbable disaccharides, rifaximin, branched chain amino acids (BCAA) and L-ornithine-L-aspartate (LOLA).29 Furthermore, ALC appears to be more well-tolerated and safe with relatively low cost
Acknowledgements The authors thank all study participants and the laboratory technicians L
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