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The glycerol phosphate pathway starts with the reaction of G-3-P with fatty acid-coenzyme A (FA-CoA) to form lysophosphatidic acid (LPA) catalyzed by glycerol-3-phosphate acyltransferase (GPAT) [44]
We also used MetaboAnalyst v5.0 (Xia Lab @ McGill University, Montreal, QC, Canada) [30] to identify the metabolites that contribute to group separation using Partial Least Squares-Discriminant Analysis (PLS-DA), heat map, and pathway analysis
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