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While the service provides significant savings and the convenience of telehealth, patients should be aware of the risks associated with compounded medications

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Division of Noncommunicable Diseases/World Health Organization/Programme of Nutrition Family and Reproductive Health

Clinicians may not be expected to find in these advances in the basic science of insulin regulation any new light shed on the clinical aspects of insulin homeostasis noted above

A retrospective study conducted at the University Health Network found that, in liver transplant recipients with diabetes, combination therapy reduced HbA1c and alanine aminotransferase levels more effectively than DPP-4 inhibitors. Additionally, two clinical trials in patients with Type 2 diabetes demonstrated that combination therapy significantly lowered HbA1c by 1.34% and 1.21%, compared to a 0.54% reduction with placebo, starting from a baseline of 8.0%. These findings suggest that combination therapy may be especially beneficial in the liver transplant population, where patients often experience weight gain and develop metabolic co-morbidities