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They should never be split, shared, or reused

Semaglutide and tirzepatide are both glucagon-like peptide-1 GLP-1 receptor agonists, which means that they work in the same way to reduce appetite and regulate blood sugar levels

Senescence induction causes a marked upregulation of p16INK4a expression, leading to cell cycle arrest in the G1 phase and thereby preserving the senescent phenotype by blocking the cyclin-dependent kinases CDK4 and CDK6, which stops the retinoblastoma protein (pRb) from being phosphorylated (Sharpless and Sherr 2015)

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