After intragastric administration of 50 and 100 mg/kg L-carnitine for 30 days, axon area, myelin sheath area, axon diameter, myelin sheath diameter, and numerical density of the myelinated axons of injured sciatic nerve were similar to normal, and the function of injured sciatic nerve also improved significantly
Local pain, erythema, or phlebitis may develop at intravenous or intramuscular injection sites, mitigated by slow administration and site rotation
In the coming years, patients and providers will have the options of newly launched biosimilars, novel GLP-1s, combination drugs, and approvals for allied indications
Maes M, Yirmyia R, Noraberg J, Brene S, Hibbeln J, Perini G, et al
Semaglutide, which is the most recently approved GLP-1R agonist, is of great interest because it can be administered orally weekly once