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When to seek medical advice : Patients should contact their GP or prescribing clinician if they experience: Lumps that are enlarging, increasingly painful, or not resolving after several weeks Signs of infection (increasing redness, warmth, purulent discharge, fever) Systemic symptoms such as malaise or fever Persistent bleeding or bruising at injection sites For urgent concerns that are not life-threatening, contact NHS 111 for advice

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doi: 152

Limonta P, Moretti RM, Marzagalli M, Fontana F, Raimondi M, Montagnani Marelli M