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Anticancer Ther

36 Although anti-obesity drugs might be a promising solution, their limited efficacy, together with possible side effects and drug interactions, highlights a constant need to find novel, efficient, and safe anti-obesity ingredients

Factor #2: PCOS improvement happens faster than expected For women with PCOS, GLP-1s create a perfect storm of fertility improvement through improved insulin sensitivity (which is often the root problem in PCOS), reduced androgen levels as testosterone and other androgens drop when insulin improves, ongoing weight loss effects where each pound lost further improves hormonal balance, and potentially direct ovarian effects as some evidence suggests GLP-1s may directly improve ovarian function

Journal of Hepatology, Volume 81, Issue 3, 492-542

For some individuals, this adjustment phase may manifest as minor skin changes