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Glucagon exerts potent lipolytic and thermogenic effects by stimulating hepatic fatty acid oxidation and BAT activity, although its hyperglycemic potential necessitates co-activation with GLP-1 to ensure net euglycemia [54]

In contrast, the triazole-based compound IIIM(S)-RS98 induces apoptosis in lung cancer cells via mitochondrial and PI3K/Akt pathways ( Figure 4 )

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