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doi:10.1016/j.jpsychires.2018.09.016 Haberka M, Mizia-Stec K, Mizia M, et al
The coq oxidoreductase fsp1 acts parallel to gpx4 to inhibit ferroptosis
To overcome the difficulties in targeting NRF2 for controlling NRF2-addicted cancers, targeting metabolic liabilities unique to NRF2-addicted cancer cells, such as dependency on exogenous NEAAs, including glutamine, is a very sensible way to achieve selective toxicity toward cancers that have fallen in NRF2 addiction
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