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Participants who completed VESPER-1 were eligible to enroll in an exploratory open-label extension that evaluated higher weekly dosing (1.6 mg, 2.4 mg) and less frequent dosing (every other week and monthly)
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The paraformaldehyde was then removed, the wells were washed three times with phosphate-buffered saline, and the coverslips then treated with mounting medium and viewed under a confocal microscope
The capacity to cross this barrier also positions ALC as a protective agent against neurodegenerative processes and brain aging
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