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Reports suggests that alogliptin can compensate for the GLP-1 decline due to cardiac overload

Lipid metabolism Lipidomic studies have shown that phosphatidylethanolamines (PEs) with arachidonic acid (AA) or its derivative adrenergic acid (AdA) are the key phospholipids for oxidation, and their peroxidation is considered a significant driver of ferroptosis [19, 21]

The future challenge of reactive oxygen species (ROS) in hypertension: from bench to bed side

Zhang MZ, Wang Y, Yao B, Gewin L, Wei S, Capdevila JH, et al

Metformin is a first-line medication and the most widely-prescribed insulin-sensitizing agent in T2DM and PCOS patients