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Lower overall bioavailability compared to injections, leading to inconsistent outcomes
Researchers reconstituting lyophilized peptides or hormones for extended studies must use bacteriostatic water, not sterile water, when the vial will be accessed more than once
The absence of marketing authorisation also means that no approved UK product information defines a human dose, indication, contraindication, adverse-effect profile or monitoring programme
The key issue is absorption
FDA Approves Soliris (eculizumab) for the treatment of patients with generalized myasthenia gravis (gMG) [press release]
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