Mounjaro indigestion can occur because tirzepatide slows the rate at which food leaves the stomach
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However, we are still in the early stages of understanding these links, and larger human studies are essential to draw firm conclusions about any mental health impacts. Semaglutide works by slowing down gut motility, or the speed at which food moves through the digestive tract, which may also have an effect on gut bacteria, according to Salhab
Artmed Nicassio L, Fracasso F, Sirago G, Musicco C, Picca A, Marzetti E, Calvani R, Cantatore P, Gadaleta MN, Pesce V (2017) Dietary supplementation with acetyl- l -carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats