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This dual mechanism affects both its efficacy and its timing requirements

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SURMOUNT-1 reported nausea in 25%, vomiting in 10%, diarrhea in 18%, constipation in 11%

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Common appetite-related changes include reduced hunger between meals, feeling full faster during meals, nausea or discomfort after rich or fatty foods, and longer stretches between feeling hungry

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Most research focuses on its ability to support the skins regenerative processes, reduce inflammation, and remodel the extracellular matrix, which are all beneficial for post-acne recovery and overall skin health

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