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This spatial heterogeneity may contribute to the partial biochemical response observed and further explain the lack of global behavioral improvement
Western blot assay Gastrocnemius muscles were collected for the detection of NLRP3, GSDMD-FL, GSDMD-N, IL-1, IL-18, CD31, and VEGF-, while HUVECs and THP-1 cells were collected for the detection of GSDMD-FL, GSDMD-N, IL-1, IL-18, and CCL11
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