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On the first and third days, frozen sections of the joint tissues were made and the invasion depth and distribution of RBITC-GLP-1RAs@NPs or RBITC-GLP-1RAs@NPs-WYRGRL in the articular cartilage were observed under a fluorescence microscope

Simultaneously, an increase in the expression of cell adhesion (E-cadherin) and apoptosis-related (Bax) proteins was noted

doi: 10.1016/j.maturitas.2011.12.016 13 LeenersBGearyNToblerPNAsarianL

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However, information related to pregnancy appears in Section 8.1 & 8.3 of the prescribing information for both Ozempic and Wegovy." Novo Nordisk has also created a Wegovy Pregnancy Registry to collect health data from women who take the GLP-1 medications during pregnancy