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Vitamin B12, also called cobalamin, is a water-soluble vitamin

This synergy occurs because the two pathways interact at multiple levels

NAD+ is the important substrate for three major enzyme families: sirtuins (SIRT1-7), poly(ADP-ribose) polymerases (PARPs), and CD38/CD157 ectoenzymes

2004 Nov-Dec;22(6):343-52

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