doi: 10.1056/NEJM197306072882312 3 ElrickHStimmlerLHladCJAraiY
Other general confounding factors noted in patients of these studies include but are not limited to obesity, alcohol, nicotine, or marijuana
Still, a noticeable number of people report warmth, flushing, or vasomotor sensations while on the drug, so the relationship deserves careful tracking rather than dismissal
In the model proposed by Lee, homocysteine is shunted away from the methionine synthesis pathway and toward the GSH synthesis pathway, creating a relative deficiency of methyl donors in order to keep up with increased demand for the glutathione needed for POP conjugation ( Fig 3 )
Patients should understand the difference between expected medication side effects and warning signs of potentially significant problems