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In an open-label phase 3 trial in 809 adults with obesity, CagriSema showed 23% weight loss at 84 weeks, meaning it lagged the 25.5% for tirzepatide, the already-approved Eli Lilly (NYSE: LLY) medicine sold as Zepbound
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Future research should focus on large-scale, well-controlled randomized trials with standardized dosing protocols, clearly defined deficiency thresholds, and long-term follow-up to strengthen the evidence base and guide clinical practice
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