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M.GhezziP.GrlachA.KietzmannT.et al (2017)

However, phenobarbital is effective and perhaps underutilized: Phenobarbital (15 mg/kg) was found to be equally effective as compared to lorazepam (0.1 mg/kg) as first-line therapy for status epilepticus in the VA-Cooperative trial

doi: 10.1007/s00125-007-0681-5 13 ZhaoHWangLWeiRXiuDTaoMKeJet al

In March 2011, the FDA placed the trial on clinical hold due to GMP compliance issues at the contract manufacturer not safety concerns with RGN-352 itself