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GLP-1 agonists work through appetite suppression and delayed gastric emptyingreducing caloric intake without directly improving mitochondrial function or insulin sensitivity at the cellular level

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Vitamin B12 supplementation is available in several forms, including oral tablets, sublingual (dissolved under the tongue) preparations, nasal sprays, and intramuscular injections (commonly known as B12 shots)

HeLa cells are originally derived from cervical cancer cells and are used extensively in scientific research

Maintenance therapy for patients with neurological involvement may also be more frequent, sometimes every two months rather than three, though this should be individualised based on clinical response