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In summary, the developed vaccine candidate induced both cellular and humoral immune responses, which are recognized as crucial for protection against S

alternative routes have unknown safety implications Efficacy : The dose-response relationship established in trials assumes subcutaneous delivery Tolerability : Gastrointestinal adverse effects (nausea, vomiting, diarrhea) are dose-dependent and may be affected by altered absorption Patients with lower body mass index or those injecting in areas with less subcutaneous fat may be at higher risk of inadvertent intramuscular injection if proper technique is not followed

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135 Therefore, the unique metabolic vulnerabilities of cancer cells, which differ from those of normal cells, can be strategically targeted to develop novel and effective therapeutic interventions

doi: 10.3390/ijms23031014 70