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The mechanism linking these effects is well-documented in the growth hormone literature
Frequently Asked Questions About Peptide Reconstitution What Is the Best Solvent for Reconstituting Peptides
Cell Stem Cell (2009) 4:31323
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No effects were seen when glucose was not administered, compatible with the idea that DPP-4 inhibition exerts an anti-hyperglycaemic effect by preventing degradation of endogenously released GLP-1 (26), subsequent studies in glucose-intolerant rodent models did show that the improved glycaemic control following in vivo DPP-4 inhibition was associated with enhanced intact GLP-1 responses to glucose challenges (2729)
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