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18 Sutterlin MW, Bussen SS, Rieger L, Dietl J, Steck T

for some, the support for the bodys repair cycle may even contribute to a more restful feeling upon waking

Since the TME can also shape therapeutic responses and resistance, a deeper understanding of TME characteristics and function is required for developing new strategies for targeting its components in patients with primary and metastatic tumors [6,7,8]