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Studies have shown that DAP and reuterin can inhibit the heterodimerization of HIF-2 with the aryl hydrocarbon receptor nuclear translocator, thereby downregulating the expression of intestinal iron absorption-related genes and subsequently limiting iron uptake (51)
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The challenge is that this reduction in calories almost always means a reduction in protein intake, because protein comes from food
Combining them might to offer the benefits of both without significantly increasing the risk of adverse effects
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